Gender mainstreaming in health sector is a commonly applied strategy for providing equal health benefits to men and women by incorporating various implications of social construction of gender with health policies. However, gender mainstreaming, to a large extent is insufficient to address the rapidly growing health problems and frequently transforming health trends- such as ageing, increase of non-communicable diseases, mental health issues, environmental hazard borne diseases etc. While women’s reproductive health is the major concern of health governance both in the national and international levels- especially in developing countries, the newly emerging health issues of women remain almost invisible and unexplored. Using secondary data analysis method, this article has opted for qualitative approach to examine data collected from existing literature and tried to find out these changing health trends of women, the reason why they are undervalued and limitations of gender mainstreaming in addressing them. At the end, it has also suggested some potential policy approaches for the national and international health governing bodies to meet the limitations.